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 Nervous tissue is the term for groups of organized cells in
the nervous system, which
 controls the body’s movements,
 sends and carries signals to and from the different parts of the body,
 has a role in controlling bodily functions such as digestion.
Nervous tissue is grouped into two main categories: neurons and
neuroglia.
Neurons, or nerves, transmit electrical impulses, while neuroglia do
not; neuroglia have many other functions including supporting and
protecting neurons.
DEFINITION
NERVOUS SYSTEM
Nervous tissue makes up the nervous system.
The nervous system is subdivided in several overlapping ways.
The central nervous system (CNS) is composed of the brain and spinal cord,
which coordinates information from all areas of the body and sends nerve
impulses that control all bodily movements.
The peripheral nervous system (PNS) consists of peripheral nerves that
branch all throughout the body. It connects the CNS to the rest of the body
and is directly responsible for controlling movements of specific parts of the
body.
Example: just before arm movement the CNS sends nerve impulses to the
PNS nerves in the arm, which causes the arm to move.
 Another subdivision of the nervous system is into the sympathetic nervous
system (SNS) and the parasympathetic nervous system (PSNS).
 The SNS activates in order to stimulate a fight-or-flight response in
an organism when that organism encounters a threat and must decide
whether to fight or flee from it. The nerves of the SNS have diverse effects on
different parts of the body.
 Activation of the SNS causes the pupils of the eyes to dilate, inhibits
digestion, increases sweat secretion, and increases the heart rate.
 Conversely, the PSNS is activated during moments of “rest and digest”, when
an organism is not facing an immediate threat. The enteric nervous system
(ENS) controls the gastrointestinal tract (digestive tract).
 Nerves of the PSNS work to stimulate activities that can occur at rest such as
digestion, waste excretion, and sexual arousal, and they also decrease the
heart rate.
This division of the nervous system, along with the SNS and PSNS, are
collectively referred to as the autonomic nervous system (ANS).
 The ANS regulates activities that are performed unconsciously; we don’t
have to think about digesting food for it to occur, for example.
By contrast, the somatic nervous system (SoNS) controls voluntary body
movements. It is made up of afferent and efferent nerves that send signals to
and from the CNS, causing voluntary muscle contraction to occur.
The cell bodies of other PNS neurons, such as the sensory neurons that
provide information about touch, position, pain, and temperature, are located
outside of the CNS, where they are found in clusters known as ganglia.
The axons of peripheral neurons that travel a common route are bundled
together to form nerves.
If you think about the roles of the three classes of neurons, you can make
the generalization that all neurons have three basic functions. These are
to:
Receive signals (or information).
Integrate incoming signals (to determine whether or not the
information should be passed along).
Communicate signals to target cells (other neurons or muscles or
glands).
These neuronal functions are reflected in the anatomy of the neuron.
THE BASIC FUNCTION OF NERVOUS
TISSUE
LOCATION
Technically they’re
present all over, with
motor neurons, different
types of sensory
neurons, and inter
neurons connecting
them and connecting
them to the brain, which
is composed of inter
neurons itself. The brain
probably has the highest
neuron-density of the
body due to being
literally made of
neurons.
CLASSIFICATION OF NERVOUS
TISSUE
Nervous Tissue
Neurons Neuroglia
Neurons are cells that can transmit signals called nerve impulses, or action
potentials. An action potential is a quick rise and fall in the electrical
membrane potential of the neuron, which transmits signals from one
neuron to the next.
NEURON
The Cell Body
The main portion of the neuron is called the soma, or cell body.
 In the center of the soma is the nucleus of the cell, which is where the
chromosomes that contain all of the genetic material are stored. This is also
the part of the cell that creates mRNA for cell replication.
Various processes (appendages or protrusions) extend from the cell body.
These include many short, branching processes, known as dendrites, and a
separate process that is typically longer than the dendrites, known as
the axon.
TYPICAL STRUCTURE OF A NEURON
TYPICAL STRUCTURE OF A NEURON
Dendrites
The first two neuronal functions, receiving and processing incoming
information, generally take place in the dendrites and cell body.
Incoming signals can be either excitatory – which means they tend to
make the neuron fire (generate an electrical impulse) – or inhibitory –
which means that they tend to keep the neuron from firing.
Most neurons receive many input signals throughout their dendritic trees.
A single neuron may have more than one set of dendrites, and may receive
many thousands of input signals. Whether or not a neuron is excited into
firing an impulse depends on the sum of all of the excitatory and inhibitory
signals it receives. If the neuron does end up firing, the nerve impulse,
or action potential, is conducted down the axon.
Axons
The dendrites tend to taper and are often covered with little bumps called
spines. In contrast, the axon tends to stay the same diameter for most of its
length and doesn't have spines.
The axon arises from the cell body at a specialized area called the axon hillock.
Finally, many axons are covered with a special insulating substance
called myelin, which helps them convey the nerve impulse rapidly. Myelin is
never found on dendrites.
Towards its end, the axon splits up into many branches and develops bulbous
swellings known as axon terminals (or nerve terminals). These axon terminals
make connections on target cells.
Synapse
The synapse is the chemical junction between the axon terminals of one neuron
and the dendrites of the next. It is a gap where specialized chemical interactions
can occur, rather than an actual structure.
The myelin sheath is the location of a number of diseases that cause
degeneration of the myelin sheath, also called demyelinating, such as:
Multiple Sclerosis
Optic Neuritisuillain-Barré syndrome
Transverse Myelitis
Central Pontine Myelinolysis
Vitamin B-12 Deficiency
Chronic Inflammatory Demyelinating Polyneuropathy
The degeneration of the myelin sheath causes degradation of the neural
impulses that are transmitted along an axon. The systems affected by this
degradation depend on the location of the degenerating myelin. For example,
multiple sclerosis (MS) affects the neurons of the spinal cord as well as the brain
leading to degradation of both motor and cognitive functioning.
DISORDERS DUE TO THE DEMYELINATION
IN MYELIN SHEATH
CLASSIFICATION OF NEURONS BASED ON
THEIR ROLES
Based on their roles, the neurons found in the human nervous system can be
divided into three classes: sensory neurons, motor neurons, and
interneurons.
Sensory neurons
Sensory neurons get information about what's going on inside and outside
of the body and bring that information into the CNS so it can be processed.
For instance, if you picked up a hot coal, sensory neurons with endings in your
fingertips would convey the information to your CNS that it was really hot.
Motor neurons
Motor neurons get information from other neurons and convey commands
to your muscles, organs and glands. For instance, if you picked up a hot coal, it
motor neurons innervating the muscles in your fingers would cause your hand
to let go.
Interneurons
Interneurons, which are found only in the CNS, connect one neuron to
another. They receive information from other neurons (either sensory neurons
or interneurons) and transmit information to other neurons (either motor
neurons or interneurons).
For instance, if you picked up a hot coal, the signal from the sensory neurons
in your fingertips would travel to interneurons in your spinal cord. Some of
these interneurons would signal to the motor neurons controlling your finger
muscles (causing you to let go), while others would transmit the signal up the
spinal cord to neurons in the brain, where it would be perceived as pain.
Interneurons are the most numerous class of neurons and are involved in
processing information, both in simple reflex circuits (like those triggered by
hot objects) and in more complex circuits in the brain. It would be
combinations of interneurons in your brain that would allow you to draw the
conclusion that things that looked like hot coals weren't good to pick up, and,
hopefully, retain that information for future reference.
Glial cells play a supporting role thus glial cells are essential to nervous
system function.
There are many more glial cells in the brain than there are neurons.
There are four main types of glial cells in the adult vertebrate nervous
system. Three of these, astrocytes, oligodendrocytes, and microglia, are
found only in the central nervous system (CNS). The fourth, the Schwann
cells, are found only in the peripheral nervous system (PNS).
GLIAL CELLS
CLASSIFICATION OF GLIAL CELLS
Astrocytes
These are the most numerous type of glial cell. In fact, they are the most
numerous cells in the brain!
Astrocytes come in different types and have a variety of functions.
They help regulate blood flow in the brain,
maintain the composition of the fluid that surrounds neurons,
regulate communication between neurons at the synapse.
During development, astrocytes help neurons find their way to their
destinations and contribute to the formation of the blood-brain barrier,
which helps isolate the brain from potentially toxic substances in the blood.
Microglia
These are related to the macrophages of the immune system and act as
scavengers to remove dead cells and other debris.
Oligodendrocytes and Schwann cells
These cells of of the CNS and the PNS share a similar function.
Both of these types of glial cells produce myelin, the insulating
substance that forms a sheath around the axons of many neurons.
Myelin dramatically increases the speed with which an action potential
travels down the axon, and it plays a crucial role in nervous system
function.
Other types of glia
in addition to the four main types the glial cells also include satellite glial cells
and ependymal cells.
Satellite glial cells
•These cover the cell bodies of neurons in PNS ganglia.
• Satellite glial cells are thought to support the function of the neurons and
might act as a protective barrier.
Ependymal cells
•These cells line the ventricles of the brain and the central canal of the spinal
cord
•They have hair-like cilia that beat to promote circulation of the cerebrospinal
fluid found inside the ventricles and spinal canal.
Nervous Tissue