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Nervous System
• The network of nerve cells and fibres which transmits nerve impulses
between parts of the body.
• The nervous system controls everything you do, including breathing,
walking, thinking, and feeling. This system is made up of your brain,
spinal cord, and all the nerves of your body. The brain is the control
center and the spinal cord is the major highway to and from the brain.
Nervous System
Neuron
• The neuron is the basic working unit of the brain, a specialized cell
designed to transmit information to other nerve cells, muscle, or
gland cells. Neurons are cells within the nervous system that transmit
information to other nerve cells, muscle, or gland cells
• Nervous system cells are called neurons. They have three distinct
parts, including a cell body, axon, and dendrites. These parts help
them to send and receive chemical and electrical signals.
Neuroglia (Glial Cells )
• Neuroglia, also called glial cell or glia, any of several types of cell that
function primarily to support neurons. … It has since been shown that
glucose, amino acids, and ions—all of which influence neuronal
function—are exchanged between the extracellular space and
neuroglial cells.
• Glial cells are found in the central nervous system (CNS) and
peripheral nervous system (PNS)
• Glial (Neuroglial) cells do not conduct nerve impulses, but, instead,
support, nourish, and protect the neurons. Glial cells are far more
numerous than neurons and, unlike neurons, are capable of mitosis.
• Schwann cells (SCs) are the main glial cells of the peripheral nervous
system which wrap around axons of motor and sensory neurons to
form the myelin sheath.
• Satellite glial cells formerly called amphicytes[1] are glial cells that
cover the surface of neuron cell bodies in ganglia of the peripheral
nervous system. Thus, they are found in sensory, sympathetic, and
parasympathetic ganglia.they provide nutrient support and
protection. They may also help to regulate the neuronal environment
and be involved in neurotransmission
• Astrocytes get their name because they are “star-shaped”. They are
the most abundant glial cells in the brain that are closely associated
with neuronal synapses. They regulate the transmission of electrical
impulses within the brain. … Metabolic support: They provide
neurons with nutrients such as lactate.
• The barrier is formed by capillary endothelial cells, surrounded by
basal lamina and astrocytic perivascular endfeet. Astrocytes provide
the cellular link to the neurons. The figure also shows pericytes and
microglial cells. A | Brain endothelial cell features observed in cell
culture
BBB
• The blood vessels that vascularize the central nervous system (CNS)
possess unique properties, termed the blood–brain barrier, which
allow these vessels to tightly regulate the movement of ions,
molecules, and cells between the blood and the brain.
• Function :
• The purpose of the blood–brain barrier is to protect against
circulating toxins or pathogens that could cause brain infections,
while at the same time allowing vital nutrients to reach the brain
• Ependymal cells line fluid-filled ventricles of the brain and the central
canal of the spinal cord. They are involved in the production of
cerebrospinal fluid, which serves as a cushion for the brain, moves
the fluid between the spinal cord and the brain, and is a component
of the choroid plexus.
• Microglia are a type of neuroglia (glial cell) located throughout the
brain and spinal cord. … As the resident macrophage cells, they act as
the first and main form of active immune defense in the central
nervous system (CNS).
• Oligodendrocytes are a type of large glial cell found in the central
nervous system. Oligodendrocytes produce the myelin sheath
insulating neuronal axons (analogous to Schwann cells in the
peripheral nervous system), although some oligodendrocytes (called
satellite oligodendrocytes) are not involved in myelination.
Nervous System,Neuron, Glial cells