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The NERVOUS SystemThe NERVOUS System
7.01 The three broad functions of7.01 The three broad functions of
the nervous system:the nervous system:
SensorySensory
– senses stimuli from both within the bodysenses stimuli from both within the body
and from the external environmentand from the external environment
IntegrativeIntegrative
– analyzes, interprets, and stores informationanalyzes, interprets, and stores information
about the stimuli it has receives from theabout the stimuli it has receives from the
sensory portion of the nervous systemsensory portion of the nervous system
MotorMotor
– responds to stimuli by some type of actionresponds to stimuli by some type of action
muscular contractionmuscular contraction
glandular secretionglandular secretion
7.02 Describe the general organization of7.02 Describe the general organization of
the nervous system.the nervous system.
Central Nervous System (CNS)Central Nervous System (CNS)
– BrainBrain
– Spinal CordSpinal Cord
Peripheral Nervous System (PNS)Peripheral Nervous System (PNS)
– Spinal Nerves (31 pairs)Spinal Nerves (31 pairs)
– Cranial Nerves (I-XII pairs)Cranial Nerves (I-XII pairs)
– SubdivisionsSubdivisions
Autonomic Nervous System (ANS) - InvolutaryAutonomic Nervous System (ANS) - Involutary
– SympatheticSympathetic
– ParasympatheticParasympathetic
Somatic Nervous System - VoluntarySomatic Nervous System - Voluntary
7.02 The Central Nervous System7.02 The Central Nervous System
(CNS)(CNS)
Brain and Spinal CordBrain and Spinal Cord
CNS FunctionCNS Function
– Sorts incoming sensorySorts incoming sensory
informationinformation
– Generates thoughts andGenerates thoughts and
emotionsemotions
– Forms and stores memoriesForms and stores memories
– Stimulates muscle contractionsStimulates muscle contractions
– Stimulates glandular secretionsStimulates glandular secretions
7.02 Peripheral Nervous System7.02 Peripheral Nervous System
(PNS)(PNS)
Spinal and Cranial NervesSpinal and Cranial Nerves
– Spinal Nerves (31 pairs)Spinal Nerves (31 pairs)
– Cranial Nerves (I-XII pairs)Cranial Nerves (I-XII pairs)
– SubdivisionsSubdivisions
Autonomic Nervous System (ANS) - InvolutaryAutonomic Nervous System (ANS) - Involutary
– SympatheticSympathetic
– ParasympatheticParasympathetic
Somatic Nervous System - VoluntarySomatic Nervous System - Voluntary
CNSCNS
PNSPNS
GreenGreen is the PNSis the PNS
CNSCNS
7.02 The Autonomic7.02 The Autonomic
Nervous System (ANS)Nervous System (ANS)
Contains sensory neurons mainly from theContains sensory neurons mainly from the
viscera that convey information to theviscera that convey information to the
CNSCNS
Contains the efferent neurons that conductContains the efferent neurons that conduct
impulses to smooth muscle, cardiacimpulses to smooth muscle, cardiac
muscle, and glandsmuscle, and glands
Unconscious controlUnconscious control
Two divisions of the ANSTwo divisions of the ANS
– Sympathetic Division - stimulatory effectSympathetic Division - stimulatory effect
– Parasympathetic Division - inhibitory effectParasympathetic Division - inhibitory effect
SympatheticSympathetic
Stimulatory.Stimulatory.
“Fight or Flight”“Fight or Flight”
ParasympatheticParasympathetic
Inhibitory.Inhibitory.
7.02 The Somatic Nervous System7.02 The Somatic Nervous System
(SNS)(SNS)
Made up of sensory neurons thatMade up of sensory neurons that
convey information from the cutaneousconvey information from the cutaneous
and special sense receptors in the head,and special sense receptors in the head,
body wall, and extremities to the CNSbody wall, and extremities to the CNS
Also contains the motor neurons fromAlso contains the motor neurons from
the CNS that conduct impulses to thethe CNS that conduct impulses to the
skeletal musclesskeletal muscles
7.03 List the functions and7.03 List the functions and
structures of neurons.structures of neurons.
The nerve cells responsible for theThe nerve cells responsible for the
special functions of the nervous systemspecial functions of the nervous system
– sensingsensing - remembering- remembering - thinking- thinking
– controlling muscle activitycontrolling muscle activity
– controlling glandular secretionscontrolling glandular secretions
Synapse - the functional relay pointsSynapse - the functional relay points
between two neurons or between abetween two neurons or between a
neuron and an effector organneuron and an effector organ
– Neuromuscular JunctionNeuromuscular Junction
– Neuroglandular JunctionNeuroglandular Junction
7.03 List the functions and7.03 List the functions and
structures of neurons.structures of neurons.
Cell Body (Soma or Perikaryon)Cell Body (Soma or Perikaryon)
– nucleus, cytoplasm, organelles of a neuronnucleus, cytoplasm, organelles of a neuron
Dendrites - tapered, highly branchedDendrites - tapered, highly branched
processes protruding from the cell bodyprocesses protruding from the cell body
– usually very shortusually very short
– AFFERENT FUNCTIONAFFERENT FUNCTION
Axons - long, thin, cylindrical processAxons - long, thin, cylindrical process
– usually myelinatedusually myelinated
– EFFERENT FUNCTIONEFFERENT FUNCTION
NeuronNeuron
NeuronsNeurons
7.03 List the functions and7.03 List the functions and
structures ofstructures of neuroglialneuroglial cells:cells:
Nervous system cells that support,Nervous system cells that support,
nurture and protect the neuronsnurture and protect the neurons
Types of Neuroglia found in theTypes of Neuroglia found in the CNSCNS
– AstrocytesAstrocytes
– OligodendrocytesOligodendrocytes
– MicrogliaMicroglia
– Ependymal CellsEpendymal Cells
Types of Neuroglia found in theTypes of Neuroglia found in the PNSPNS
– Neurolemmocytes (Schwann Cells)Neurolemmocytes (Schwann Cells)
– Satellite CellsSatellite Cells
7.03 Astrocytes (Astroglia)7.03 Astrocytes (Astroglia)
Star-shaped cells with many processesStar-shaped cells with many processes
Forms the Blood Brain Barrier (BBB)Forms the Blood Brain Barrier (BBB)
Forms the pia mater covering the brainForms the pia mater covering the brain
and spinal cord.and spinal cord.
Soaks up excess ions and toxinsSoaks up excess ions and toxins
Participate in brain developmentParticipate in brain development
Facilitates repair for CNS traumaFacilitates repair for CNS trauma
7.03 Astrocyte7.03 Astrocyte
7.03 Microglia7.03 Microglia
Small phagocytic cells that protect theSmall phagocytic cells that protect the
central nervous system by engulfingcentral nervous system by engulfing
and invading microbesand invading microbes
Clears awayClears away
debris fromdebris from
dead cellsdead cells
7.03 Oligodendrocytes7.03 Oligodendrocytes
(Oligodendroglia)(Oligodendroglia)
Oligo- small or fewOligo- small or few
Small glial cells with few processesSmall glial cells with few processes
Form a supporting network around theForm a supporting network around the
neurons by twining around neuronsneurons by twining around neurons
and producing a lipid and proteinand producing a lipid and protein
wrapping around the neuronswrapping around the neurons
((myelin sheathmyelin sheath))
6.03 Oligodendrocyte6.03 Oligodendrocyte
7.03 Ependymal Cells7.03 Ependymal Cells
Neuroglia cells lineNeuroglia cells line
the brain ventriclesthe brain ventricles
and the central canaland the central canal
of the spinal cordof the spinal cord
Form and circulateForm and circulate
cerebral spinal fluidcerebral spinal fluid
(CSF)(CSF)
7.03 Neuroglia of the PNS7.03 Neuroglia of the PNS
(Schwann and Satellite cells)(Schwann and Satellite cells)
Schwann CellsSchwann Cells - Neurolemmocytes- Neurolemmocytes
– Cells responsible for producing the myelinCells responsible for producing the myelin
sheaths around the PNS neuronssheaths around the PNS neurons
Satellite CellsSatellite Cells
– Similar to astrocytesSimilar to astrocytes
– Structural supportStructural support
– soaks up excess ionssoaks up excess ions
and toxinsand toxins
7.03 Schwann Cell Myelination7.03 Schwann Cell Myelination
7.03 Myelination7.03 Myelination
7.03 Myelination7.03 Myelination
The process of developing or producingThe process of developing or producing
a Myelin Sheatha Myelin Sheath
Insulates the axon of a neuronInsulates the axon of a neuron
Increases the speed of nerve impulseIncreases the speed of nerve impulse
conductionconduction
– CNS - oligodendrocytesCNS - oligodendrocytes
– PNS - neurolemmocytes (Schwann Cells)PNS - neurolemmocytes (Schwann Cells)
Guillain-Barre syndrome and MultipleGuillain-Barre syndrome and Multiple
Sclerosis are involved the destruction ofSclerosis are involved the destruction of
the myelin sheaths around the nervethe myelin sheaths around the nerve
7.04 Contrast white and gray7.04 Contrast white and gray
matter of nervous tissue.matter of nervous tissue.
White MatterWhite Matter - the aggregation of- the aggregation of
myelinatedmyelinated processes from manyprocesses from many
neuronsneurons
– Visible upon freshly dissected brain orVisible upon freshly dissected brain or
spinal tissuespinal tissue
– White color is due to myelinationWhite color is due to myelination
Gray MatterGray Matter -- unmyelinatedunmyelinated nerve cellnerve cell
bodies, axons, dendrites, ganglia, andbodies, axons, dendrites, ganglia, and
axon terminalsaxon terminals
– Appears gray because of lack of myelinAppears gray because of lack of myelin
7.04 Gray and White Matter7.04 Gray and White Matter
7.05 Describe the location, and7.05 Describe the location, and
function of CSF.function of CSF.
(ventricles, subarachnoid space)(ventricles, subarachnoid space)
Cavities within the brainCavities within the brain
Lateral ventricles (2) - located within eachLateral ventricles (2) - located within each
hemisphere in the cerebrumhemisphere in the cerebrum
Third ventricle - a vertical slit between theThird ventricle - a vertical slit between the
lateral ventricles and inferior to the rightlateral ventricles and inferior to the right
and left halves of the thalamusand left halves of the thalamus
Fourth ventricle - space between theFourth ventricle - space between the
brainstem and the cerebellumbrainstem and the cerebellum
7.05 Describe the location, and7.05 Describe the location, and
function of CSF.function of CSF.
(Choroid Plexus)(Choroid Plexus)
Network of capillaries in the walls of theNetwork of capillaries in the walls of the
ventriclesventricles
Covered with ependymal cells that form theCovered with ependymal cells that form the
cerebrospinal fluidcerebrospinal fluid
These ependymal cells are so close togetherThese ependymal cells are so close together
they form the blood-brain barrier.they form the blood-brain barrier.
– Selectively permeable barrierSelectively permeable barrier
– Protects the brain and spinal cord fromProtects the brain and spinal cord from
potentially harmful substances in the bloodpotentially harmful substances in the blood
7.05 Blood Supply to the Brain7.05 Blood Supply to the Brain
One of the most metabolically activeOne of the most metabolically active
organs in the bodyorgans in the body
Makes up only 2-3% of body weight butMakes up only 2-3% of body weight but
uses about 20% of available Ouses about 20% of available O22 at restat rest
Well supplied with OWell supplied with O22 and nutrientsand nutrients
Only nutritional source for brainOnly nutritional source for brain
metabolic activity is glucosemetabolic activity is glucose
Capillaries in the brain are much lessCapillaries in the brain are much less
leaky than other capillaries in the bodyleaky than other capillaries in the body
and form a blood brain barrierand form a blood brain barrier
7.05 Describe the function of CSF.7.05 Describe the function of CSF.
Mechanical ProtectionMechanical Protection
– Serves as a shock absorbing mediumServes as a shock absorbing medium
– Buoys the brain so it literally floats withinBuoys the brain so it literally floats within
the cranial cavitythe cranial cavity
Chemical ProtectionChemical Protection
– Provides an optimal chemical environmentProvides an optimal chemical environment
for neural signalingfor neural signaling
CirculationCirculation
– Acts as a medium for exchange of nutrientsActs as a medium for exchange of nutrients
and waste products between the blood andand waste products between the blood and
nervous tissuenervous tissue
7.05 Ventricles of the Brain7.05 Ventricles of the Brain
7.057.05
FlowFlow
ofof
Cerebro-Cerebro-
SpinalSpinal
FluidFluid
(CSF)(CSF)
7.057.05
FlowFlow
ofof
Cerebro-Cerebro-
SpinalSpinal
FluidFluid
HydrocephalusHydrocephalus
Blocked Cerebral AqueductBlocked Cerebral Aqueduct
7.06 Identify the structures responsible for7.06 Identify the structures responsible for
the maintenance and protection of thethe maintenance and protection of the
central nervous system.central nervous system.
Protected by the cranial bones and the cranial meningesProtected by the cranial bones and the cranial meninges
– Dura MaterDura Mater - outer layer- outer layer
– ArachnoidArachnoid - middle layer- middle layer
– Pia MaterPia Mater - inner layer- inner layer
Also protected byAlso protected by cerebrospinal fluid (CSF)cerebrospinal fluid (CSF)
– fluid that nourishes and protects the brain and spinal cordfluid that nourishes and protects the brain and spinal cord
– continuously circulates through the subarachnoid spacecontinuously circulates through the subarachnoid space
around the brain and throughout the cavities within thearound the brain and throughout the cavities within the
brainbrain
7.06 Meninges7.06 Meninges
Connective tissue covering foundConnective tissue covering found
around the brain and spinal cordaround the brain and spinal cord
Three layered membraneThree layered membrane
– Dura Mater - outer most layerDura Mater - outer most layer
dense irregular connective tissuedense irregular connective tissue
– Arachnoid - middle layerArachnoid - middle layer
spider web arrangement of collagen fibersspider web arrangement of collagen fibers
– Pia Mater - inner most meningesPia Mater - inner most meninges
very delicate layer of thin tissuevery delicate layer of thin tissue
7.06 Meninges of the Brain7.06 Meninges of the Brain
7.067.06
MeningesMeninges
of theof the
Spinal CordSpinal Cord
Dura MaterDura Mater
ArachnoidArachnoid
-Subarachnoid Space-Subarachnoid Space
Pia MaterPia Mater
The BRAINThe BRAIN
7.07 Identify the four principle7.07 Identify the four principle
parts of the brain.parts of the brain.
cerebrum, cerebellum, brain stem,cerebrum, cerebellum, brain stem,
diencephalondiencephalon
One of the largest organs in the bodyOne of the largest organs in the body
Controls all mental functionsControls all mental functions
Component of the CNSComponent of the CNS
Composed of over 100 billion neuronsComposed of over 100 billion neurons
Comprises 2-3% of body weightComprises 2-3% of body weight
Utilizes over 20% of body’s energyUtilizes over 20% of body’s energy
CEREBRUMCEREBRUM - occupies most of the- occupies most of the
cranium and is divided into right and leftcranium and is divided into right and left
halves called hemisphereshalves called hemispheres
CEREBELLUMCEREBELLUM - the posterior-inferior- the posterior-inferior
portion of the brainportion of the brain
BRAIN STEMBRAIN STEM - consists of the medulla- consists of the medulla
oblongata, thoblongata, thee pons, and the midbrainpons, and the midbrain
– it is continuous with the spinal cordit is continuous with the spinal cord
DIENCEPHALONDIENCEPHALON - located above the- located above the
brainstem, composed primarily of the:brainstem, composed primarily of the:
– ThalamusThalamus -- HypothalamusHypothalamus
The BrainThe Brain
7.08 Describe the functions of7.08 Describe the functions of
the three structures of thethe three structures of the
brain stem.brain stem.
The most inferior portion of the brainThe most inferior portion of the brain
Connects the brain to the spinal cordConnects the brain to the spinal cord
Composed of Three AreasComposed of Three Areas
– The Medulla OblongataThe Medulla Oblongata
– The PonsThe Pons
– The MidbrainThe Midbrain
7.08 The Medulla Oblongata7.08 The Medulla Oblongata
Most inferior portion of the brain stemMost inferior portion of the brain stem
Connects the brain stem to the spinalConnects the brain stem to the spinal
cordcord
Respiratory Center ***Respiratory Center ***
– Adjusts rhythm and depth of breathingAdjusts rhythm and depth of breathing
Cardiovascular Center ***Cardiovascular Center ***
– Regulates heart rate and contraction forceRegulates heart rate and contraction force
– Influences vasoconstriction andInfluences vasoconstriction and
vasodilationvasodilation
Also controls coughing, vomiting,Also controls coughing, vomiting,
swallowing, and hiccuppingswallowing, and hiccupping
The Medulla OblongataThe Medulla Oblongata
The Medulla OblongataThe Medulla Oblongata
7.08 The Pons7.08 The Pons
Lies superior to the medulla oblongataLies superior to the medulla oblongata
Together with the respiratory center inTogether with the respiratory center in
the medulla helps control respirationthe medulla helps control respiration
The PonsThe Pons
7.08 The Midbrain7.08 The Midbrain
Superior to the ponsSuperior to the pons
Connects the brain stem to theConnects the brain stem to the
diencephalondiencephalon
The MidbrainThe Midbrain
Pons and MidbrainPons and Midbrain
7.09 Describe the structures and7.09 Describe the structures and
functions of the diencephalon.functions of the diencephalon.
Area of the brain containing the:Area of the brain containing the:
– ThalamusThalamus
– HypothalamusHypothalamus
7.09 The Thalamus7.09 The Thalamus
Oval structure that makes up 80% of theOval structure that makes up 80% of the
diencephalondiencephalon
Comprised of a pair of oval massesComprised of a pair of oval masses
(mostly gray matter)(mostly gray matter)
PrinciplePrinciple relay stationrelay station between thebetween the
various sections of the brainvarious sections of the brain
The ThalamusThe Thalamus
7.09 The Hypothalamus7.09 The Hypothalamus
A small portion of the diencephalonA small portion of the diencephalon
located below the thalamuslocated below the thalamus
One of the main regulators ofOne of the main regulators of
homeostasis in the bodyhomeostasis in the body
Lacks a blood brain barrierLacks a blood brain barrier
Partially protected by the sella turcicaPartially protected by the sella turcica
of the sphenoid boneof the sphenoid bone
7.09 Functions of the7.09 Functions of the
HypothalamusHypothalamus
Coordinates Nervous System andCoordinates Nervous System and
Endocrine System activities to maintainEndocrine System activities to maintain
HomeostasisHomeostasis
– Thirst, Hunger, SatietyThirst, Hunger, Satiety
– Sleep Patterns and Waking StatesSleep Patterns and Waking States
– Sex Drive, Maturation, Aggression, andSex Drive, Maturation, Aggression, and
RageRage
– influences movement of food through theinfluences movement of food through the
Gastrointestinal TractGastrointestinal Tract
– production and secretion of hormones Thatproduction and secretion of hormones That
control other Endocrine Glandscontrol other Endocrine Glands
The HypothalamusThe Hypothalamus
HypothalamusHypothalamus
7.10 Describe the locations and functions7.10 Describe the locations and functions
of theof the four lobesfour lobes of the cerebrum.of the cerebrum.
Largest division of the brainLargest division of the brain
Occupies most of the craniumOccupies most of the cranium
Accounts for 85% of brain massAccounts for 85% of brain mass
Divided into right and left hemispheresDivided into right and left hemispheres
– Longitudinal FissureLongitudinal Fissure
– Corpus CallosumCorpus Callosum
Cerebral cortex - the outer surface areaCerebral cortex - the outer surface area
of the cerebrumof the cerebrum
– Composed mainly of gray matterComposed mainly of gray matter
– Contains billions of neuronsContains billions of neurons
The CerebrumThe Cerebrum
7.10 Describe the locations and7.10 Describe the locations and
functions of the four lobes of thefunctions of the four lobes of the
cerebrum.cerebrum.
Named after the bones that cover themNamed after the bones that cover them
– Frontal LobeFrontal Lobe
– Parietal LobeParietal Lobe
– Temporal LobeTemporal Lobe
– Occipital LobeOccipital Lobe
7.10 Frontal Lobe7.10 Frontal Lobe
Motor AreasMotor Areas
– Controls movement of voluntary skeletalControls movement of voluntary skeletal
musclesmuscles
Association AreasAssociation Areas
– Carry on high level intellectual processingCarry on high level intellectual processing
Problem SolvingProblem Solving - Reasoning- Reasoning - Planning- Planning
ConcentrationConcentration - Memory- Memory - Behavior- Behavior
EmotionsEmotions - Expressions- Expressions
7.10 Parietal Lobe7.10 Parietal Lobe
Sensory AreasSensory Areas
– Interprets sensations such as:Interprets sensations such as:
– touch - pressure - pain on the surface of thetouch - pressure - pain on the surface of the
skinskin
Association AreasAssociation Areas
– Understanding of speechUnderstanding of speech
– Using words to express thoughts andUsing words to express thoughts and
feelingsfeelings
7.10 Temporal Lobe7.10 Temporal Lobe
Sensory AreasSensory Areas
– Hearing and balanceHearing and balance
Association AreasAssociation Areas
– Interpret sensory experiencesInterpret sensory experiences
– Memory of visual scenes - music - smellsMemory of visual scenes - music - smells
and other complex sensory patternsand other complex sensory patterns
7.10 Occipital Lobe7.10 Occipital Lobe
Sensory AreasSensory Areas
– Visual processing and interpretationVisual processing and interpretation
Association AreasAssociation Areas
– Combines visual images with sensoryCombines visual images with sensory
experienceexperience
7.11 Explain the major7.11 Explain the major
functions of the cerebellum.functions of the cerebellum.
Second largest portion of the brainSecond largest portion of the brain
Occupies the inferior and posteriorOccupies the inferior and posterior
aspects of the cranial cavityaspects of the cranial cavity
Processes sensory informationProcesses sensory information
– BalanceBalance - Coordination- Coordination
– Maintains postural equilibriumMaintains postural equilibrium
The CerebellumThe Cerebellum
Cerebellum and BrainstemCerebellum and Brainstem
7.11 Cerebellar Test7.11 Cerebellar Test
Finger to Finger TestFinger to Finger Test
Finger to Nose TestFinger to Nose Test
Holme’s Sign (overreaction)Holme’s Sign (overreaction)
Romberg’s Test (Eyes Closed)Romberg’s Test (Eyes Closed)
7.12 Sequence the major events7.12 Sequence the major events
when the nerve impulsewhen the nerve impulse
(action potential) is initiated(action potential) is initiated
and transmitted through a neuron.and transmitted through a neuron.
The transmission of nerveThe transmission of nerve
(electrical) impulses from(electrical) impulses from
nervous tissue to othernervous tissue to other
nervous tissue, organs,nervous tissue, organs,
glands, and muscles.glands, and muscles.
7.12 Neuron Membrane Potential7.12 Neuron Membrane Potential
7.12 Neuron Action Potential7.12 Neuron Action Potential
7.12 Transmission of Nerve7.12 Transmission of Nerve
ImpulsesImpulses
An electrical event due to movement ofAn electrical event due to movement of
ions across a membraneions across a membrane
Also called an action potentialAlso called an action potential
– Lasts about 1 msec (1/1000 of a second)Lasts about 1 msec (1/1000 of a second)
– Dependent upon diameter of the axonDependent upon diameter of the axon
A-(thick myelin/fast), B-(thin myelin/moderate),A-(thick myelin/fast), B-(thin myelin/moderate),
C-(unmyelin/slow) fibersC-(unmyelin/slow) fibers
larger diameter axons - 0.4 msec (1/2500 sec)larger diameter axons - 0.4 msec (1/2500 sec)
– 2500 impulses per second2500 impulses per second
smaller diameter axons - 4 msec (1/250 sec)smaller diameter axons - 4 msec (1/250 sec)
– 250 impulses per second250 impulses per second
7.12 All or None Principle7.12 All or None Principle
If depolarization reaches a threshold, anIf depolarization reaches a threshold, an
action potential (impulse) is conductedaction potential (impulse) is conducted
Each action potential (impulse) isEach action potential (impulse) is
conducted at maximumconducted at maximum
strength unless there arestrength unless there are
toxic materials withintoxic materials within
the cell or the membranethe cell or the membrane
has been disruptedhas been disrupted
7.12 Neuron Impulse7.12 Neuron Impulse
7.12 Transmission of Nerve7.12 Transmission of Nerve
Impulses at SynapsesImpulses at Synapses
Most nervous conduction is fromMost nervous conduction is from
neuron to neuron (interneurons - 90%)neuron to neuron (interneurons - 90%)
Types of SynapsesTypes of Synapses
– Axon to dendriteAxon to dendrite
– Axon to somaAxon to soma
– Axon to axonAxon to axon
Two ways to transmit impulses across aTwo ways to transmit impulses across a
synapsesynapse
– Electrical SynapsesElectrical Synapses
– Chemical SynapsesChemical Synapses
7.127.12
NeuronNeuron
ActionAction
PotentialPotential
7.12 Types of Impulse Conduction7.12 Types of Impulse Conduction
Continuous ConductionContinuous Conduction - step by step- step by step
depolarization of each sequential,depolarization of each sequential,
adjacent area of of the nerve celladjacent area of of the nerve cell
membranemembrane
– typical of unmyelinated nerve fiberstypical of unmyelinated nerve fibers
– type of action potential in muscle fiberstype of action potential in muscle fibers
Saltatory ConductionSaltatory Conduction - the jumping of- the jumping of
an action potential across specializedan action potential across specialized
neurofibril nodes along the axonneurofibril nodes along the axon
– Nodes of RanvierNodes of Ranvier
7.12 Nerve Conduction7.12 Nerve Conduction
7.13 Explain the role of each of7.13 Explain the role of each of
the components of a reflex arc.the components of a reflex arc.
((reflexreflex,, reflex arc:reflex arc: receptorreceptor,,
sensory neuronsensory neuron,, associationassociation
[interneuron] neuron[interneuron] neuron,,
motor neuronmotor neuron,, effectoreffector))
7.13 The Reflex Arc:7.13 The Reflex Arc: receptor, sensoryreceptor, sensory
neuron, association [interneuron] neuron,neuron, association [interneuron] neuron,
motor neuron, effectormotor neuron, effector
A response by the body involving onlyA response by the body involving only
the body segment being affected andthe body segment being affected and
the spinal cordthe spinal cord
– Brain does not have to be involvedBrain does not have to be involved
Receptor - the distal end of a sensoryReceptor - the distal end of a sensory
neuron (dendrite)neuron (dendrite)
– Responds to a specific stimulusResponds to a specific stimulus
a change in internal or external environmenta change in internal or external environment
– Triggers a nerve impulseTriggers a nerve impulse
Sensory Neuron - the neuron located inSensory Neuron - the neuron located in
the gray matter of the spinal cordthe gray matter of the spinal cord
– conducts impulses from the receptor to theconducts impulses from the receptor to the
spinal cordspinal cord
Integrating Center - a region within theIntegrating Center - a region within the
CNS (spinal cord or brain) thatCNS (spinal cord or brain) that
interprets the information from theinterprets the information from the
sensory neuron and initiates ansensory neuron and initiates an
appropriate responseappropriate response
Motor Neurons - the neurons arisingMotor Neurons - the neurons arising
from the integrating center that relay afrom the integrating center that relay a
nerve impulse to the part of the bodynerve impulse to the part of the body
that will respond to the stimulusthat will respond to the stimulus
Effector - the part of the body thatEffector - the part of the body that
responds to the motor nerve impulseresponds to the motor nerve impulse
(usually a muscle or a gland)(usually a muscle or a gland)
– Effector - skeletal muscle - somatic reflexEffector - skeletal muscle - somatic reflex
– Effector - cardiac, smooth muscle, or glandEffector - cardiac, smooth muscle, or gland
-visceral reflex-visceral reflex
7.13 The Peripheral7.13 The Peripheral
Nervous System (PNS)Nervous System (PNS)
Connects sensory receptors, muscles,Connects sensory receptors, muscles,
and glands in the peripheral parts of theand glands in the peripheral parts of the
body to the central nervous systembody to the central nervous system
Consists of cranial and spinal nervesConsists of cranial and spinal nerves
Afferent Neurons (Sensory)Afferent Neurons (Sensory)
– conduct nerve impulses from sensoryconduct nerve impulses from sensory
receptors toward the CNSreceptors toward the CNS
Efferent Neurons (Motor)Efferent Neurons (Motor)
– conduct nerve impulses fromconduct nerve impulses from
the CNS to muscles and glandsthe CNS to muscles and glands
CNSCNS
PNSPNS
7.13 The Reflex Arc7.13 The Reflex Arc
7.13 Reflex arc (Reflexes).7.13 Reflex arc (Reflexes).
Fast, predictable, automatic responsesFast, predictable, automatic responses
to changes in the environment that helpto changes in the environment that help
maintain homeostasismaintain homeostasis
Somatic Reflexes - involve skeletalSomatic Reflexes - involve skeletal
musclesmuscles
Visceral (Autonomic) Reflexes - involveVisceral (Autonomic) Reflexes - involve
responses of smooth muscles, the heart,responses of smooth muscles, the heart,
and glandsand glands
Involve the spinal nervesInvolve the spinal nerves
7.13 Reflex Arc Examples7.13 Reflex Arc Examples
Stretch Reflex - results in theStretch Reflex - results in the
contraction of a muscle if it has beencontraction of a muscle if it has been
stretched suddenlystretched suddenly
Tendon Reflex - results in theTendon Reflex - results in the
contraction of a muscle when a tendoncontraction of a muscle when a tendon
is stretched suddenlyis stretched suddenly
Flexor (Withdrawal) Reflex - suddenFlexor (Withdrawal) Reflex - sudden
contraction and removal of a bodycontraction and removal of a body
segment as a result of a pain stimulussegment as a result of a pain stimulus
7.13 Tendon Reflex7.13 Tendon Reflex
7.137.13
WithdrawalWithdrawal
ReflexReflex
also calledalso called
FlexorFlexor
/Withdrawal/Withdrawal
ReflexReflex
07.14 Identify the following07.14 Identify the following
diseases or disorders of thediseases or disorders of the
nervous system.nervous system.
(ALS, Alzheimer’s, bacterial(ALS, Alzheimer’s, bacterial
meningitis, cerebral palsy,meningitis, cerebral palsy,
epilepsy, multipleepilepsy, multiple
sclerosis, Parkinson’s,sclerosis, Parkinson’s,
Guillain-Barre syndrome)Guillain-Barre syndrome)
7.14 Amyotrophic Lateral7.14 Amyotrophic Lateral
Sclerosis (ALS)Sclerosis (ALS)
Also known as Lou Gehrig’s DiseaseAlso known as Lou Gehrig’s Disease
A relatively rare neurological disorderA relatively rare neurological disorder
A syndrome marked by muscular weaknessA syndrome marked by muscular weakness
and atrophy with spasticity and hyperflexionand atrophy with spasticity and hyperflexion
due to degeneration of the motor neurons ofdue to degeneration of the motor neurons of
the spinal cord, medulla, and cortexthe spinal cord, medulla, and cortex
A degenerative diseaseA degenerative disease
No known cureNo known cure
7.14 Alzheimer’s Disease (AD)7.14 Alzheimer’s Disease (AD)
Disabling neurological disorder thatDisabling neurological disorder that
effects about 11% of the populationeffects about 11% of the population
Fourth leading cause of brain deathFourth leading cause of brain death
among the elderlyamong the elderly
A chronic, organic, mental disorder, aA chronic, organic, mental disorder, a
form of pre-senile dementia due toform of pre-senile dementia due to
atrophy of neurons of the frontal andatrophy of neurons of the frontal and
occipital lobesoccipital lobes
AD patients usually die fromAD patients usually die from
complications due to being bedriddencomplications due to being bedridden
7.14 Bacterial Meningitis7.14 Bacterial Meningitis
Infection of the meninges by theInfection of the meninges by the
bacterium Haemophilus Influenzaebacterium Haemophilus Influenzae
Usually affects children under age 5Usually affects children under age 5
Symptoms include severe headachesSymptoms include severe headaches
and feverand fever
Can lead to brain damage and evenCan lead to brain damage and even
death if not treateddeath if not treated
Brudzinki’s SignBrudzinki’s Sign