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TOPIC:VITREOUS
DR SAKSHI SAHNI
ASST PROF
DEPTT OF OPHTHALMOLOGY
ASCOMS
ď‚§ Functions :
ď‚§ Serves mainly optical functions
ď‚§ Mechanically stabilises the eyeball
ď‚§ Pathway for nutrients to reach the lens and
retina.
Embryology :
ď‚§ vitreous body Derived from neuroectoderm
of optic disc.
ď‚§ During stages of development ,secondary
vitreous fills the cavity , primary vitreous
along with hyaloid vessels is pushed
anteriorly and ultimately disappears.
ď‚§ Tertiary vitreous is developed from
neuroectoderm in the ciliary region and is
represented by the ciliary zonules.
ď‚§ Vitreous base : part of the vitreous 4mm
across ora serrata.
ď‚§ It is the strongest attachment.
ď‚§ Anterior face of the vitreous cortex is
attached to the posterior surface of the lens
ď‚§ In rest of the retina , vitreous cortex is loosely
attached to the ILM being comparatively less
loose along the major retinal vessels
ď‚§ Vitreous opacities
ď‚§ Extremely annoying as they cast a shadow on
the retina and
ď‚§ Appear as black spot moving in and out ofVF
ď‚§ Patient complains of moving flies or insects
infront of eyes
ď‚§ Pathologically these are clumped cells or
strands of vitreous gel which become less
transparent than rest of the vitreous
VITREOUS OPACITIES :
ď‚§ Developmental opacities:
ď‚§ Located in the canal of cloquet
ď‚§ Are remnants of hyaloid system
ď‚§ Degenerative changes :
ď‚§ Asteroid hyalosis
ď‚§ Synchisis schintillans
ď‚§ Amyloid degeneration
ď‚§ Unilateral
ď‚§ Old age
ď‚§ asymptomatic
ď‚§ It affects the damaged eyes which have
suffered from trauma ,VH, inflammatory
diseases in the past.
ď‚§ Pathognomic feature is crystals settle down
with every pause after stir.
ď‚§ Golden shower of rain.
ď‚§ Can occur at any age
Amyloid degeneration:
ď‚§ Amyloidosis is a localised or systemic
condition in which there is extracellular
deposition of fibrillary protein
ď‚§ Involvement of vitreous occurs in familial
amyloidosis
ď‚§ Characterised by polyneuropathy ,prominent
corneal nerves and pupillary light near
dissociation.
ď‚§ Vitreous opacities take a typical GLASS
WOOL appearance.
ď‚§ these get attached to the posterior lens by thick
footplates
ď‚§ Can lead to severe visual impairment
ď‚§ Rx : vitrectomy
ď‚§ RED CELL OPACITIES:
ď‚§ Cause isVH
ď‚§ TUMOUR CELL OPACITIES:
ď‚§ Free floating opacities in patients of RB,
reticulum cell sarcoma and intraocular
lymphomas
Vitreous cyst:
ď‚§ Congenital
ď‚§ Acquired
ď‚§ Cause : trauma , inflammation.
ď‚§ Can be : pigmented : arises from ciliary body
pigment epithelium
ď‚§ or non pigmented: arise from the remnants of
primary hyaloid vascular system.
ď‚§ Can be free floating or attached to optic disc
ď‚§ Rx: laser cystotomy or vitrectomy .
ď‚§ Can present as
ď‚§ Bergmeister papilla : seen as a tuft at the
optic disc
ď‚§ Mittendorf dot: seen on the post lens surface
Terson syndrome:
ď‚§ Combination of intraocular and subarachnoid
haemorrhage secondary to aneurysmal
rupture from ant communicating artery.
ď‚§ Bilateral
ď‚§ Preretinal or intraretinal haem. Breaks up into
the vitreous
ď‚§ Rx not required
ď‚§ Prognosis is usaually good
ď‚§ Anterior vitrectomy: removal of ant.Vitreous
ď‚§ Core vitrectomy; removal of central bulk of
vitreous
ď‚§ Subtotal and total vitrectomy:
ď‚§ TECHNIQUESOFVITRECTOMY:
ď‚§ Open sky vitrectomy: performed through the
primary wound to manage the disturbed
vitreous in cataract surgery, aphakic
keratoplasty and globe rupture.
ď‚§ Pars plana vitrectomy:
ď‚§ One port :done with multifunction vitrectomy
probe ( infusion ,suction and cutter(VSC)
ď‚§ Three port: illumination probe
ď‚§ Infusion cannula
ď‚§ Cutter n suction cannula.
Vitreous substitutes
ď‚§ Used in vitreoretinal surgery
ď‚§ Function :
ď‚§ To restore IOP
ď‚§ To provide intraocular tamponade
ď‚§ Silicone oil:
ď‚§ Benefit is that it allows more controlled
retinal manipulation during vitreoretinal
surgery.
Posterior vitreous
detachment:
separation of cortical vitreous from retina
anywhere posterior to vitreous base
Cause : collagen cross linking and selective
loss of retinal adherence are the primary
events.
s/s:
Flashes of light /photopsia occurs because if
mechanical stimulation of retina due to
vitreous traction.
ď‚§ Floaters /cogweb
ď‚§ Biomicroscopic examination:
ď‚§ Collapsed vitreous: behind the lens and an
optically clear space between detached
posterior hyaloid face and retina .
ď‚§ Weiss ring : ring of attachment of vitreos to
optic disc.(pathognomic)
Complications:
ď‚§ Retinal breaks
ď‚§ VH
ď‚§ Retinal haem
ď‚§ RD
ď‚§ Management:
ď‚§ Uncomplicated PVD: F/U
ď‚§ Retinal tear complicating PVD requires LPC
ď‚§ VH /RD
ď‚§ THANK YOU