Spina bifida is a neural tube defect characterized by improper formation of the spine and spinal cord, which can range from mild to severe forms, such as spina bifida occulta and myelomeningocele. Risk factors include genetic predisposition, folate deficiency, and maternal health issues, with symptoms varying by severity and type. Preventative measures, particularly folic acid supplementation before and during early pregnancy, can significantly reduce the occurrence of this defect.