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SAMPLING METHODS IN
RESEARCH METHODOLOGY
Dr. Satavisha Kundu
Post Graduate Student,
Department Of Conservative Dentistry And Endodontics,
Manipal College Of Dental Sciences, Manipal.
CONTENTS
1. Sampling – Definition
2. Objectives of Sampling
3. Types of Sampling Methods
4. Comparison between Probability and Non-Probability Sampling
5. Difference between Sampling Error and Sampling Bias
6. Advantages and Limitations of Sampling
7. Applications in Dental and Medical Research
8. Overview of randomization and its types
9. External validity
10.Ethical Considerations in Sampling
11.Conclusion
12.References
WHAT IS SAMPLING? ( DEFINITION )
Sampling is a technique of selecting individual members or a subset of the population to make
statistical inferences from them and estimate the characteristics of the whole population.
Different sampling methods are widely used by researchers in market research so that they
do
not need to research the entire population to collect actionable insights.
It is also a time-convenient and a cost-effective method and hence forms the basis of
any research design.
KEY OBJECTIVES OF SAMPLING :
1.Reduce Costs and Time: Sampling allows for efficient data collection by focusing on
a representative subset.
2.Improve Accuracy: Smaller, well-designed samples can lead to more accurate,
focused data collection.
3.Ensure Representativeness: By carefully selecting a sample, researchers can
ensure that the findings are relevant to the larger population.
Muhammad Hassan, 2024
SAMPLING METHODS
The entire set of cases from which
researcher sample is drawn in called the
POPULATION. Since, researchers neither
have time nor the resources to analysis the
entire population so they apply sampling
technique to reduce the number of cases.
CHOOSE SAMPLING TECHNIQUE
PROBABILITY SAMPLING:
• In probability sampling, every member of the population has a predetermined
chance of being chosen for inclusion in the sample.
• In the context of this study, the population is considered to be relatively
homogeneous due to the fact that each member of the population is a potential
respondent for the research
• Has the greatest freedom from bias but may represent the most costly sample in
terms of time and energy for a given level of sampling error (Brown, 1947).
TYPES OF PROBABILITY SAMPLING
• The simple random sampling means that every case of the population has an equal
probability of inclusion in sample.
• Example: A school administrator randomly selects 50 students from a list of all students to
survey about cafeteria satisfaction.
Methods of doing SRS
1. Lottery method ( chit – mix – pick )
2. Random Number Table (Table of random nos./ computer)
Types
3. With Replacement (SRSWR)
4. Without Replacement (SRSWOR) (more common)
1. SIMPLE RANDOM SAMPLING ( SRS )
2. SYTEMATIC SAMPLING
• A starting point is randomly selected, and then every kth individual is chosen from a list. This method
is often used when there’s a fixed pattern or order in the population list.
• Example: A researcher wants to survey a population of 1,000 people and decides to select every
10th person on a sorted list after a random start.
• The determination of sample size and calculation of sampling interval can be achieved through the
use of a specific formula K = N/n represents the Kth element, where ,
• N = total population, n = sample size, K = interval (gap)
TYPES
1. Linear Systematic Sampling (most common)
2. Circular Systematic Sampling
3. STRATIFIED RANDOM SAMPLING
• Stratified sampling is where the population is divided into strata (or subgroups) and a random sample
is taken from each subgroup. A subgroup is a natural set of items. Subgroups might be based on
company size, gender or occupation (to name but a few). Stratified sampling is often used where
there is a great deal of variation within a population. Its purpose is to ensure that every stratum is
adequately represented (Ackoff, 1953).
• Example: In a study on employee satisfaction, researchers divide employees into departments (e.g.,
sales, HR, finance) and randomly select employees from each department.
TYPES :
1. Proportionate Stratified Sampling (most important)
2. Disproportionate Stratified Sampling
4. CLUSTER SAMPLING
• Cluster sampling is where the whole population is divided into clusters or groups. Subsequently, a
random sample is taken from these clusters, all of which are used in the final sample (Wilson, 2010).
Cluster sampling is advantageous for those researchers whose subjects are fragmented over large
geographical areas as it saves time and money (Davis, 2005).
• Example: In a national health study, a researcher randomly selects specific cities (clusters) and
surveys all residents within those cities.
• MULTI-STAGE SAMPLING, also referred to as multi-stage cluster sampling, is a sophisticated
variant of cluster sampling that facilitate primary data collection by dividing large clusters of
population into smaller clusters through several stages.
• Eg. School Survey: Select schools → select classes → select students.
NON- PROBABILITY SAMPLING:
• In non-probability sampling, individuals are selected based on specific characteristics or
convenience rather than random selection. This method is suitable for exploratory research
where generalizability is less critical.
• Non probability sampling is often associated with case study research design and qualitative
research. With regards to the latter, case studies tend to focus on small samples and are
intended to examine a real-life phenomenon, not to make statistical inferences in relation to
the wider population (Yin, 2003).
TYPES OF NON-PROBABILITY SAMPLING
1. CONVENIENCE SAMPLING
• Convenience sampling is selecting participants because they are often readily and easily
available. Typically, convenience sampling tends to be a favored sampling technique among
students as it is inexpensive, fast and an easy option compared to other sampling techniques
(Ackoff, 1953).
• For example, using friends or family as part of sample is easier than targeting unknown
individuals.
Example: A psychology student surveys classmates because they are easily accessible and
available for quick data collection.
2. PURPOSIVE OR JUDGMENTAL SAMPLING
• Purposive or judgmental sampling is a strategy in which particular settings persons or
events are selected deliberately in order to provide important information that cannot be
obtained from other choices (Maxwell, 1996). It is where the researcher includes cases
or participants in the sample because they believe that they warrant inclusion.
• Participants are selected based on specific criteria or characteristics relevant to the
study’s purpose.
• Example: In a study on the effects of leadership training, a researcher selects
participants who hold managerial positions to gain insights specific to leaders.
Purposive sampling:
• Improves relevance to research objective
• Enhances data quality in qualitative studies
1. Both are non-probability methods with risk of bias.
2. Convenience is used for ease (often quantitative), while purposive is used for
targeted selection (mainly qualitative).
3. Choice depends on study objective.
3. SNOWBALL SAMPLING
• Snowball sampling is a non-random sampling method that
uses a few cases to help encourage other cases to take part
in the study, thereby increasing sample size. This approach
is most applicable in small populations that are difficult to
access due to their closed nature, e.g. secret societies and
inaccessible professions (Breweton and Millward, 2001).
• Types :
1. Linear Snowball (A → B → C → D → E)
2. Exponential Non-Discriminative
3. Exponential Discriminative
QUOTA SAMPLING
• Quota sampling is a non-random sampling technique in which participants are chosen on the
basis of predetermined characteristics so that the total sample will have the same distribution
of characteristics as the wider population (Davis, 2005).
• Example: A researcher studying consumer preferences might set a quota to survey 50 men
and 50 women in a shopping mall
• Types
1. Controlled Quota
2. Uncontrolled Quota
 Compares probability vs non-probability sampling
Probability sampling methods enhance representativeness, whereas non-
probability methods are more feasible but prone to bias.
DIFFERENCE BETWEEN SAMPLING ERROR AND SAMPLING BIAS
ASPECT SAMPLING ERROR SAMPLING BIAS
Definition
Difference between sample result
and true population value due to
chance variation
Systematic error caused by unfair
selection of participants
Cause
Small sample size or random
variation
Faulty sampling method or unequal
selection
Nature Random Systematic
Occurs When
Sample does not perfectly
represent population by chance
Certain groups are overrepresented
or underrepresented
Can It Be Measured? Yes Difficult to measure exactly
Can It Be Reduced? Yes Yes, by proper study design
Main Solution Increase sample size Use proper sampling technique
Example
Randomly selecting unusually
healthy people by chance
Excluding rural population from
survey
Kultar Singh et al., 2022
TYPE EXPLANATION
Self-selection bias
People volunteer themselves, often having similar
characteristics
Coverage bias Non-participants differ from participants
Undercoverage bias Some groups are poorly represented
Advertising / Pre-screening bias Recruitment method influences participant selection
TYPES OF SAMPLING BIAS
COMMON TYPES OF SAMPLING ERRORS
TYPE EXPLANATION
Population specification error Wrong population is identified
Sampling frame error Wrong subgroup is targeted
Selection error Participants choose themselves to participate
Sampling mistake Sample fails to represent population properly
Kultar Singh et al., 2022
METHOD PURPOSE
Define target population clearly Ensures correct participant selection
Use proper sampling frame Makes sample closer to population
Use simple questionnaires Improves response rate
Follow-up non-respondents Reduces missing data bias
Proper study design Minimizes systematic errors
METHOD BENEFIT
Increase sample size Improves representativeness
Use proportional sampling Reflects population structure accurately
Understand population demographics Helps proper sample selection
HOW TO MINIMIZE SAMPLING ERROR
HOW TO PREVENT SAMPLING BIAS
Kultar Singh et al., 2022
Random
sampling:
• Equal chance
→ most
reliable
Stratified
sampling:
• reduces
sampling error
Convenience:
• Cheap but not
representation
Random
sampling allows
estimation of
population
parameters with
known
confidence,
unlike non-
probability
methods.
WHEN TO USE EACH SAMPLING METHOD( PROBABILITY)
1.Simple Random Sampling: Use when you need a fully representative sample, especially if
the population is homogeneous and a sampling frame is available.
2.Stratified Sampling: Best when studying specific subgroups within a population, as it
ensures representation across key characteristics.
3.Systematic Sampling: Suitable when you have a large population list and need a simple
yet systematic approach, especially if the list has no inherent order.
4.Cluster Sampling: Useful for large, geographically dispersed populations; ideal when it’s
impractical to survey individuals directly.
NON - PROBABILITY
1.Convenience Sampling: Ideal for exploratory studies, pilot tests, or when time and
resources are limited.
2.Quota Sampling: Use when studying demographic or categorical diversity, especially
when you need specific representation within the sample.
3.Snowball Sampling: Ideal for reaching hidden, hard-to-reach, or marginalized
populations.
4.Purposive Sampling: Best when studying a specific, well-defined population or a unique
group that directly relates to the research question.
EXAMPLES OF SAMPLING IN RESEARCH STUDIES
1.Education Study
1. Objective: Investigate student study habits across grade levels.
2. Sampling Method: Stratified sampling, where students are divided into grades (strata) and
randomly sampled from each grade.
2.Healthcare Study
1. Objective: Examine patient satisfaction in a hospital network.
2. Sampling Method: Cluster sampling, where hospitals (clusters) are selected, and all patients
within selected hospitals are surveyed.
CONTD…
3. Consumer Research
1. Objective: Understand shopping preferences among young adults.
2. Sampling Method: Convenience sampling, where young adults at a popular mall are surveyed.
4. Social Study
3. Objective: Study the experiences of refugees in a new country.
4. Sampling Method: Snowball sampling, where initial participants (refugees) refer others in their
community.
TIPS FOR CHOOSING THE RIGHT SAMPLING METHOD
1.Define Your Research Goals: Clarify whether you need a representative sample or a specific target
group to meet the objectives.
2.Consider Resources: Time, budget, and accessibility influence the feasibility of sampling methods.
3.Evaluate Population Characteristics: Large, diverse populations may require stratified or cluster
sampling, while homogeneous populations might benefit from simple random sampling.
4.Assess Generalizability: If generalizing results to a larger population is important, prioritize probability
sampling methods.
5.Address Ethical Concerns: Ensure ethical considerations for sensitive populations, especially when
using snowball or purposive sampling.
APPLICATIONS IN DENTAL RESEARCH
1. Clinical Trials (Randomized Controlled Trials)
• Sampling is used to select and allocate
participants into control and experimental groups.
• Random sampling ensures equal chance of
selection and reduces bias.
• Testing new materials, drugs, techniques
• Example :
• Comparing bond strength of fibre posts
• Testing new irrigants or sealers
2. Epidemiological Studies
•Studying disease prevalence in large population
•Example:
• Dental caries prevalence in school children
• Periodontal disease in rural vs urban
populations
Common Sampling used:
•Stratified sampling → age groups, gender
•Cluster sampling → selecting schools/villages
4. Rare Conditions / Special Groups
Used when the target population is specific or
limited.
•Example:
• Oral cancer patients
• TMJ disorders
• Medically compromised patients
Sampling used:
•Purposive sampling → selecting specific cases
•Snowball sampling → patient referrals
3. Hospital-Based Studies
Sampling is used to select patients from
outpatient or inpatient departments for
clinical research.
Example:
Evaluating success rates of root canal
treatments in a dental college setup.
Convenience sampling is commonly used
due to ease of access.
5. Questionnaire & Survey Studies
Sampling is used to collect data on
knowledge, attitude, and practices.
•Example:
• Patient satisfaction after treatment
• Awareness about oral hygiene
Sampling used:
•Quota sampling → equal males/females
•Convenience sampling
6. In-vitro Studies
Sampling involves selection of extracted teeth or
specimens based on specific criteria.
•Example:
• Testing bond strength, microleakage , fracture
resistance.
Sampling used:
•Teeth selected based on criteria
→ This is basically purposive sampling
RANDOMIZATION
1. Randomization ensures that each patient has an equal chance of receiving any of
the treatments under study.
2. It generates comparable intervention groups, which are alike in all important
aspects except for the intervention each group receives.
3. It eliminates selection bias and balances the groups with respect to known and
unknown confounding variables.
4. It also forms the basis for statistical tests used in analyzing the data.
KP Suresh, 2011.
1. SIMPLE RANDOMIZATION
•Randomization based on a single sequence of random
assignments.
•Maintains complete randomness of assignment of a subject to a
particular group.
•Methods include:
• Flipping a coin
• Shuffled deck of cards
• Throwing a dice
• Random number tables or computer-generated random
numbers
•Simple and easy to implement.
•May result in unequal number of participants among groups in small
sample size studies.
2. Covariate Adaptive
Randomization
•Recommended for small to
moderate size clinical research.
•A new participant is assigned by
considering:
• Specific covariates
• Previous assignments of
participants
•Uses minimization method to reduce
imbalance among covariates.
•Helps achieve treatment balance
when several prognostic factors are
present
TYPES OF RANDOMIZATION :
2. BLOCK RANDOMIZATION
•Designed to randomize subjects into groups that result
in equal sample sizes.
•Ensures balance in sample size across groups over
time.
•Blocks are small and balanced with predetermined
group assignments.
•Block size should be a multiple of the number of
groups.
•Helps achieve balance, especially in small clinical trials.
•Covariate imbalance may still occur between groups.
3. STRATIFIED RANDOMIZATION
•Used to control and balance the influence of covariates.
•Achieves balance among groups in terms of baseline
characteristics.
•Separate blocks are generated for each combination of
covariates.
•Simple randomization is then performed within each
block.
•Useful in smaller clinical trials.
•Becomes difficult when many covariates must be
controlled.
KP Suresh, 2011.
EXTERNAL VALIDITY
Definition
External validity refers to the generalization of research
findings, either from a sample to a larger population or
to settings and populations other than those studied.
Generalization
External validity is related to the “generalizability of
research findings.” It asks whether findings will hold
“beyond the particulars of time, place, and
methodology.”
Two Meanings of External Validity
1. Generalizing from a sample to a larger population
2. Generalizing across settings, times, and populations
Campbell and Stanley Definition
To what populations, settings, treatment variables, and
measurement variables can this effect be generalized?
JEFFREY W. LUCAS , 2003 .
Theory and External Validity
General knowledge is theoretical knowledge. Findings
alone cannot produce general knowledge without theory.
Role of Theory
The key component of external validity is theory. External
validity depends on the relationship between theory and
methods.
Experiments and External Validity
Experiments are often considered lower in external validity
because:
• They use convenience samples
• Conditions are artificial
• Mostly undergraduate students are used
Author’s Argument
The article states that if findings do not generalize, it may
indicate “a shortcoming of the theory” rather than a
problem with experimental methodology.
Sampling and External Validity
Probability sampling may help in generalizing to a larger
population, but no methodological procedures can allow
for generalization across settings and populations.
Artificiality in Experiments
Artificial settings help researchers “eliminate variables that
are not relevant” and focus only on theoretically
meaningful aspects.
Replication
Each successful replication increases external validity.
Repeated support in different settings increases
confidence in theory.
5 Criteria for Assessing External Validity
1. Construct validity – measures reflect theoretical
concepts
2. Relevance – study meets scope conditions
3. Reproducibility – findings repeat under same conditions
4. Consistency – findings support theory
5. Confirmatory status – theory supported in diverse tests
Conclusion
External validity is foremost a theoretical issue and can
only be addressed by an examination of the interplay
between theory and methods.
JEFFREY W. LUCAS , 2003 .
ETHICAL CONSIDERATIONS IN SAMPLING
Ethical Principle Description
Fair Selection of Participants
No discrimination based on gender, caste,
or socioeconomic status. Sample should
represent the population.
Avoidance of Bias
Avoid selecting only “easy” or favorable
cases. Use randomization to reduce bias.
Informed Consent
Participants must be informed about
purpose, procedures, risks, and benefits
before inclusion.
Ethical Principle Description
Protection of Vulnerable Groups
Extra care for children, elderly, and medically
compromised patients. Guardian consent
required when needed.
Privacy & Confidentiality
Protect patient data and ensure no disclosure
of identity.
Right to Withdraw
Participants can leave the study at any time
without pressure or penalty.
Minimizing Harm
Avoid exposing participants to unnecessary
risks. Ensure safety in experimental
procedures.
Ethical Approval
Study must be approved by Institutional
Ethics Committee (IEC) before starting.
CONCLUSION
Sampling is a cornerstone of research design,
allowing researchers to make informed
conclusions about populations through
carefully selected samples. Whether using
probability or non-probability sampling,
understanding each method’s strengths and
limitations can help researchers choose the
best approach for their study. With well-chosen
sampling methods, researchers can collect
reliable data, make meaningful inferences, and
contribute valuable insights to their fields.
REFERENCES
• Ackoff RL. The design of social research. Chicago: University of Chicago Press; 1953.
• Bartlett JE, Kotrlik JW, Higgins CC. Organizational research: determining appropriate sample size
in survey research. 2001.
• Brewerton P, Millward L. Organizational research methods. London: SAGE; 2001.
• Brown GH. A comparison of sampling methods. J Mark. 1947;6:331–337.
• Bryman A, Bell E. Business research methods. Oxford: Oxford University Press; 2003.
• Davis D. Business research for decision making. Australia: Thomson South-Western; 2005.
• Fowler FJ. Survey research methods. Newbury Park (CA): SAGE; 2002.
• Ghauri P, Grønhaug K. Research methods in business studies. Harlow: FT/Prentice Hall; 2005.
• Gill J, Johnson P, Clark M. Research methods for managers. London: SAGE; 2010.
• Malhotra NK, Birks DF. Marketing research: an applied approach. Harlow: FT/Prentice Hall; 2006.
• Maxwell JA. Qualitative research design: an interactive approach. London: SAGE; 1996.
• Wilson J. Essentials of business research: a guide to doing your research project. London: SAGE; 2010.
• Yin RK. Case study research: design and methods. Newbury Park (CA): SAGE; 2003.
• Zikmund WG. Business research methods. Dryden: Thomson Learning; 2002.
• Creswell JW, Creswell JD. Research design: qualitative, quantitative, and mixed methods approaches. 5th ed.
Thousand Oaks (CA): SAGE; 2018.
• Babbie E. The practice of social research. 15th ed. Boston: Cengage Learning; 2020.
• Fowler FJ. Survey research methods. 5th ed. Thousand Oaks (CA): SAGE; 2014.
• Lohr SL. Sampling: design and analysis. 2nd ed. Boca Raton (FL): Chapman and Hall/CRC; 2021.
• Patton MQ. Qualitative research & evaluation methods. 4th ed. Thousand Oaks (CA): SAGE; 2015.
• Makwana D, Engineer P, Dabhi A, Chudasama H. Sampling methods in research: a review. Int J Trend Sci Res
Dev. 2023;7(3):762.
• Taherdoost H. Sampling methods in research methodology: how to choose a sampling technique for research. Int J
Acad Res Manag. 2016;5(2):18–27.
• Hassan M. Sampling methods: types, techniques and examples. 2024 Mar 26.
THANK YOU