Perianal - Anatomy
•Rectum is ~ 15cms in length. Inner mucosa, submucosa then inner
circular and outer longitudinal muscle layers
• The internal sphincter is continuation of the inner circular muscle layer,
External sphincter continuation of the outer longitudinal muscle layer.
• Superior border of external sphincter fuses with puborectalis forming a
sling originating at the pubis and coming around the rectum.
• Intersphincteric groove is the space between internal and external
sphincter, fibrous continuation of the longitudinal smooth muscle rectum
• 6-10 anal glands lie in this space, each gland has a duct that discharges
into the anal crypt of the dentate line.
• Dentate line union between embryological ectoderm and endoderm and
is transition between rectal mucosa above and transitional epithelium
below. Also the division between neurovascular and lymphatic supply
into two routes.
4.
Perianal Abscess Pathophysiology
Acuteanorectal abscess Chronic anal fistula
Incidence
• 1 in 10 000 M:F 3:1 most common in 30-50s
Aetiology
• Cryptoglandular hypothesis anal fistulae (Parks &
Eisenhammer)
• Associated conditions: e.g. Crohn’s disease, trauma, TB,
malignancy.
• Acute anorectal non-cryptoglandular abscesses (Eisenhammer)
5.
Anorectal Sepsis
56%
21%
3%
3%
Superficial fistula16%
(% from Marks & Ritchie
1977, Classification of 769
fistulae)
(% from Prasad,
Read & Abrican
1981, 506
patients)
9%
48%
22%
12%
Submucos
al
abscess
4%
Diagnosis of AnorectalSepsis
• Examination
• Signs of inflammation
• EUA
• Proctosigmoidoscopy
• Investigation
• Proctoscopy & sigmoidoscopy (+/- under
anaesthesia)
• EUA under anaesthetic as 10
diagnostic
procedure.
8.
Diagnosis of AnorectalSepsis
• Techniques useful in the assessment of complicated fistulous
disease.
• Fistulography
• CT
• Anal endoultrasound
• MRI: High concordance with operative findings (St
Mark’s study 86%)
9.
Abscess - Management
•Perianal, Ischiorectal
• Incision and Drainage
• Packs, drains
• Salt baths
• Intersphincteric
• Lay open internal sphincter
• Up to dentate line, higher if extension
Evaluation - Imaging
•Fistulography
• <25% accuracy
• CT
• abscess
• U/S
• assess sphincters
• MRI
• 86% concordance with operative findings for presence of
1o
track, 2o
extensions and abscess, 97% for horseshoeing
14.
Surgical Treatment ofAnal Fistula
• Fistulotomy
• Setons
• Advancement flaps*
• Other techniques
• Fibrin glue*
• Fistulotomy & immediate reconstruction of the divided musculature, with
10
wound closure*.
• Fistulectomy
• Defunctioning colostomy
• *Need to eradicate acute sepsis before more complex procedures
undertaken for anal fistula
15.
Setons
• Potential actionsof the seton
• Act as a drain for acute sepsis
• To allow resolution of inflammation prior to definitive
fistula surgery
• Role in staged fistulotomy
• Delineation of the amount of muscle caudal to the
fistulous track
• Cutting & Chemical setons:
• Controlled division of the enclosed sphincter
mechanism with minimal separation of the
transected ends.
Editor's Notes
#2 The anal canal is 4cm in length it extends from the anorectal junction to anal verge.
The external sphincter shown to be a continuous sheet of muscle by Goligher. (a cylinder of skeletal muscle innervated by the inferior rectal nerve and perineal branch of the 4th sacral nerve).
#3 The anal canal is 4cm in length it extends from the anorectal junction to anal verge.
The external sphincter shown to be a continuous sheet of muscle by Goligher. (a cylinder of skeletal muscle innervated by the inferior rectal nerve and perineal branch of the 4th sacral nerve).
#4 Cryptoglandular hypothesis anal fistulae (Parks & Eisenhammer)
Diseased anal gland in the intersphincteric space
Associated conditions: e.g. Crohn’s disease, trauma, TB, malignancy.
Acute anorectal non-cryptoglandular abscesses (Eisenhammer)
Submucous abscess (infected haemorrhoids, sclerotherapy, trauma)
Mucocutaneous abscess (infected haematoma)
Perianal abscess (follicular skin infection)
Some ischiorectal abscesses (primary infection or foreign body related)
Pelvirectal supralevator abscess (originating in pelvic disease)
-Eisenhammer proposed that an intramuscular anal gland became infected and because of subsequent infective obstruction of its connecting duct, it was unable to
drain spontaneously into the anal canal.
-Parks found cystic dilatation of anal glands in eight of 30 consecutive cases of anal fistula.
He attributes this to either acquired duct dilatation or a congenital abnormality and suggested that it was a precursor toinfection within a mucin-filled cavity.
Rickard ANZ J. Surg. 2005; 75: 64–72
#5 Possible pathways of fistula following anal gland sepsis.
Marks and Ritchie 1977 study of 769 fistulae.
#6 EUA for patient with acute pain. Can do in patients with fistula generally.
#7 No signs of external inflammation e.g. the intersphincteric abscess
EUA (where severe pain precludes rectal examination). Remembering Goodsall’s rule.
#8 Fistulography: Kuijpers & Schulpen, 25 patient study comparing operative findings with fistulographic appearances; found fistulography to be inaccurate in 84% of patients. (Has a role in defining an extrasphincteric track)
Investigation
Proctoscopy & sigmoidoscopy (+/- under anaesthesia)
EUA under anaesthetic as 10 diagnostic procedure.
Techniques useful in the assessment of complicated fistulous disease.
Fistulography: concerns over its accuracy.
CT: limited by poor sphincter resolution, difficulty in determining pathology in relation to the levator muscles , (radiation & contrast media required)
Anal endoultrasound: limited focal range making evaluation beyond the sphincters difficult to assess.
MRI: High concordance with operative findings (St Mark’s study 86%)
STIR (short tau inversion recovery) sequencing highlights presence of pus & granulation tissue, no contrast media required.
Endo-anal coil
#14 Chemical seton, used in India, weekly re-insertion of a specially prepared thread. Plant derived.
Others gentamicin beads, coring out surgery.
Defunctioning colostomy: consider in the patient with uncontrolled sepsis complicating a suprasphincteric fistula or transsphincteric fistula.
Special considerations in Crohn’s disease> abscesses: for larger deep cavities us of a mushroom catheter to facilitate drainage and irrigation. Crohn’s anal fistulae: preliminary seton drainage, then rectal advancement flap ± covering stoma.
#15 Staged fistulotomy: eg with a transsphincteric fistula with supralevator extensions into the rectum. Differing approaches e.g. divide the upper sphincter laying open the tract then 2 months later divide the seton enclosed muscle.