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Drug study- Paracetamol and Cefuroxime Na

Paracetamol is used for mild pain or fever. It works by blocking pain impulses and inhibiting prostaglandin synthesis. The dosage is 250/5ml every 4 hours for children, with a maximum of 5 doses in 24 hours. Nurses should advise not using it for marked or prolonged fever without a prescriber's direction. Cefuroxime is a second-generation cephalosporin used for respiratory, urinary, and skin infections. It works by inhibiting cell wall synthesis. The dosage is 500mg every 8 hours. It is contraindicated in those with hypersensitivity to it or other cephalosporins, and should be used cautiously in those with penicillin aller

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XVI. Drug Study NAME OF MACHANISM OF DOSAGE INDICATIONS CONTRA- ADVERSE NURSING ALERT THE DRUG Generic ACTION Thought to Dosage: Mild pain or INDICATIONS -Contra- REACTION -Hematologic: -Use liquid form for children Name: produce 250/5ml fever indicated in Hemolytic and patients who difficulty Paracetamol analgesia by patient Anemia, of swallowing. blocking pain Frequency: hypersensitivity Leukopenia, -In children don’t exceed Brand impulses by q4h to drug. five (5) doses in 24h. Name: inhibiting Tempra synthesis of Classification: in patients with -Hepatic: only for short-term use; prostaglandin in Non opioids long-term Jaundice urge them to consult the CNS or of analgesics and alcohol use of other substances antipyretics alcohol -Metabolic: children for longer than 5 that sensitize pain because hypoglycemia days or adults for longer receptors to therapeutic stimulation. The doses cause -Skin: rash, -Tell parents/patient not to drug may relieve hepatotoxicity urticaria use for marked fever (temp fever through in these higher than 103.1F or central action in patients. 39.5C), fever persisting Neutropenia, -Use cautiously -Advise parents that drug is prescriber if giving to than 10 days. the hypothalamic longer than 3 days, or heat-regulating recurrent fever unless center. directed by prescriber. 24
NAME OF MECHANISM DOSAGE INDICATIONS CONTRA- ADVERSE NURSING ALERT
THE DRUG OF ACTION INDICATIONS REACTION Generic Second- Dosage: -Serious lower -Contraindicated -GI: diarrhea, -Before giving drug, Name: generation 500mg respiratory tract in patient with nausea, ask patient/parents if Cefuroxime cephalosporin infection, UTI, hypersensitivity to anorexia, he is allergic to Sodium that inhibits Frequency: skin structure drug or other vomiting penicillins or cell- wall q8h infections cephalosporin. -Hematologic: cephalosporin. -Use cautiously in hemolytic -Obtain specimen for Brand synthesis, Name: promoting Classification: patient anemia, C/S test before giving Zinacef osmotic Second hypersensitivity to thrombocytopeni first dose. instability, generation penicillin because a, eosinophilia -Tablets may be usually Cephalosporin of possibility of -Skin: crushed, if absolutely cross sensitivity maculopapular necessary, for patient with other beta- and who can’t swallow lactam antibiotics. erythematous tablets. Tablets can be . rashes, urticarial, dissolved in juices, pain, chocolate or milk, temperature however, the drug has elevation, a bitter taste that is anaphylaxis, difficult to mask, even hypersensitivity with food. reaction -Don’t confuse drug bactericidal. 25 with other cephalosporins that
sound alike. -Tell patient to take drug as prescribed, even after he feels better. -Instruct patient to take oral form with food. -Instruct patient to notify prescriber about rash, loose stool, diarrhea or evidence of superinfection.
Contraindicated in patient with hypersensitivity to drug or other cephalosporin. -Use cautiously in patient hypersensitivity to penicillin because of possibility of cross sensitivity with other beta- lactam antibiotics. . -CV: phlebitis, thrombophlebitis -GI: diarrhea, nausea, anorexia, vomiting -Hematologic: hemolytic anemia, thrombocytopenia, eosinophilia -Skin: maculopapular and erythematous rashes, urticarial, pain, sterile abcesses, temperature elevation, anaphylaxis, hypersensitivity reaction -Before giving drug, ask patient/parents if he is allergic to penicillins or cephalosporin. -Obtain specimen for C/S test before giving first dose. -For IM use, inject deep into a large muscle, such as gluteus maximus or the side of the thigh. -Absorption of oral drug is enhanced by food. -Tablets may be crushed, if absolutely necessary, for patient who can’t swallow tablets. Tablets can be dissolved in juices, chocolate or milk, however, the drug has a bitter taste that is difficult to mask, even with food. -Don’t confuse drug with other cephalosporins that sound alike. -Tell patient to take drug as prescribed, even after he feels better. -Instruct patient to take oral form with food. -Instruct patient to notify prescriber about rash, loose stool, diarrhea or evidence of superinfection. 26
Contraindicated in patient with hypersensitivity to drug or other cephalosporin. -Use cautiously in patient hypersensitivity to penicillin because of possibility of cross sensitivity with other beta- lactam antibiotics. . -CV: phlebitis, thrombophlebitis -GI: diarrhea, nausea, anorexia, vomiting -Hematologic: hemolytic anemia, thrombocytopenia, eosinophilia -Skin: maculopapular and erythematous rashes, urticarial, pain, sterile abcesses, temperature elevation, anaphylaxis, hypersensitivity reaction -Before giving drug, ask patient/parents if he is allergic to penicillins or cephalosporin. -Obtain specimen for C/S test before giving first dose. -For IM use, inject deep into a large muscle, such as gluteus maximus or the side of the thigh. -Absorption of oral drug is enhanced by food. -Tablets may be crushed, if absolutely necessary, for patient who can’t swallow tablets. Tablets can be dissolved in juices, chocolate or milk, however, the drug has a bitter taste that is difficult to mask, even with food. -Don’t confuse drug with other cephalosporins that sound alike. -Tell patient to take drug as prescribed, even after he feels better. -Instruct patient to take oral form with food. -Instruct patient to notify prescriber about rash, loose stool, diarrhea or evidence of superinfection. 26