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yasmina-bioinfo/README.md

👋 Hi, I'm Yasmina Soumahoro

Biologist, Biology educator & future bioinformatician exploring epigenetics in neurobiology. 🧬
Biologiste, enseignante passionnée et future bioinformaticienne explorant l’épigénétique en neurobiologie. 🧬


🧠 About Me

I’m a biology teacher transitioning into bioinformatics research to explore how epigenetic mechanisms influence neural development, stress responses, and cancer progression.
I’m passionate about understanding how experiences leave molecular marks that can shape life across generations.

FR 🇫🇷 :
Je suis enseignante en biologie et je me reconvertis dans la recherche en bioinformatique afin d’explorer comment les mécanismes épigénétiques influencent le développement neuronal, la réponse au stress et la progression du cancer.
Je cherche à comprendre comment les expériences de vie peuvent laisser des empreintes moléculaires durables à travers les générations.


🧬 Research Interests / Domaines de recherche

  • 🧠 Neuroepigenetics / Neuroépigénétique : how stress and environment regulate gene expression in the brain
    → comment le stress et l’environnement régulent l’expression des gènes dans le cerveau
  • 🧫 Cancer Epigenomics / Épigénomique du cancer : methylation, chromatin remodeling, and tumor biology
    → méthylation, remodelage de la chromatine et biologie tumorale
  • 💻 Computational Biology / Biologie computationnelle : genomic data analysis, motif discovery, and sequence patterns
    → analyse de données génomiques, recherche de motifs et séquences caractéristiques

🧩 Current Learning Path / Parcours d’apprentissage

Building solid foundations in:
Python Genomics Epigenetics Data%20Science

  • Algorithmic thinking in bioinformatics
  • Data visualization & reproducible research
  • Genomic data science & Biopython practice

FR 🇫🇷 :
Je développe des compétences solides en :

  • Raisonnement algorithmique appliqué à la bioinformatique
  • Visualisation et analyse reproductible des données biologiques
  • Sciences des données génomiques et apprentissage de Biopython

###🧩 Mini-Projects / Mini-Projets

Project / Projet Description Tools / Outils
PatternMatching DNA motif search algorithm / Recherche de motifs dans l’ADN Python, CSV
SkewArray GC skew visualization in genomes / Visualisation du déséquilibre GC dans les génomes Python, Matplotlib
GCContent GC content analysis in DNA sequences / Analyse du pourcentage de GC dans des séquences ADN Python, CSV, Matplotlib
ReverseComplement EN: Compute the reverse complement of a DNA sequence with validation and file workflow.
FR: Calcul du reverse complement d’une séquence ADN avec gestion d’erreurs et lecture/écriture de fichiers.
Python
MotifFinding Finding all 1-based motif positions in a DNA sequence (pattern matching). Part of my bioinformatics learning roadmap. Python
FASTA-Essentials Multi-FASTA analysis: GC%, heatmap, boxplot, CSV export. BioPython, Pandas & visualization tools. Python Biopython Pandas Matplotlib Seaborn
Human_Trauma_Epigenetics_GSE72680 DNA methylation (Illumina 450K) analysis of trauma exposure in humans. Includes raw-to-processed pipeline, metadata extraction, QC, visualisation and PCA. Python Pandas Matplotlib Jupyter
GSE147058_DNA_Methylation_Analysis Reproducible workflow testing & exploratory DNA methylation analysis. Python · Jupyter · Pandas · Seaborn · GEOparse
RNAseq_AIRWAY_MINI Full RNA-seq workflow: library QC, log2(CPM), PCA, DESeq2, annotated DEGs, volcano & heatmap. Python R
GSE83931_miniFASTQ Reproducible RNA-seq workflow (Salmon → tximport → DESeq2) on mouse (mm10), built alongside the Johns Hopkins Coursera transcriptomics course. R Bioconductor RNA-seq

🌱 Next Steps / Prochaines étapes

  • Deepen my expertise in genomic data science and epigenetics
  • Apply bioinformatics to neuroscience and oncology
  • Collaborate on open research linking biology, computation, and education

FR 🇫🇷 :

  • Approfondir mon expertise en sciences des données génomiques et épigénétique
  • Appliquer la bioinformatique à la neuroscience et à l’oncologie
  • Collaborer à des projets ouverts reliant biologie, informatique et éducation

📫 Connect with Me / Me contacter


“Epigenetics teaches us that our experiences leave molecular traces — understanding them is understanding ourselves.”
« L’épigénétique nous enseigne que nos expériences laissent des traces moléculaires — les comprendre, c’est mieux nous comprendre. »
Yasmina Soumahoro

Pinned Loading

  1. FASTA-Essentials FASTA-Essentials Public

    Analysis of stress- and epigenetics-related genes using real multi-FASTA data (GC%, heatmap, boxplot, Biopython & Pandas).

    Python

  2. GSE147058_DNA_METHYLATION_ANALYSIS GSE147058_DNA_METHYLATION_ANALYSIS Public

    Exploratory DNA methylation analysis of GEO dataset GSE147058, with reproducibility testing based on a prior workflow (GSE72680).

    Jupyter Notebook

  3. Human_Trauma_Epigenetics_GSE72680 Human_Trauma_Epigenetics_GSE72680 Public

    DNA methylation analysis of trauma-related samples (GSE72680).

    Jupyter Notebook

  4. PatternMatching PatternMatching Public

    Python implementation of classical pattern-matching algorithms for DNA sequences, including exact motif search and basic genomic string processing.

    Python

  5. RNAseq_AIRWAY_MINI RNAseq_AIRWAY_MINI Public

    Mini RNA-seq project using Python (QC) and R/DESeq2 (differential expression). Full workflow with PCA, heatmap, volcano plot, DEG tables, and annotated results.

    Jupyter Notebook

  6. GSE83931_miniFASTQ GSE83931_miniFASTQ Public

    Reproducible RNA-seq analysis (Salmon, tximport, DESeq2) — mouse dataset from Johns Hopkins Coursera course

    HTML