I have a "game" that manages its own time loop using requestAnimationFrame. I have ported it to angular2, and it works really well except that I experience pretty severely degraded performance over time. When I capture CPU profiles Zone ends up replacing the idle time that was there when the page loaded.

I'm not sure what to make of it, but it's very easy to reproduce--just open the page and take a profile, then wait a minute and take another profile.

Example: http://justindujardin.github.io/angular2-rpg