Skill: VCF Annotator

SKILL.md: skills/vcf-annotator/SKILL.md (spec complete)

What it does

Annotates VCF variants using VEP, ClinVar, and gnomAD with ancestry-aware allele frequency context.

Implementation scope

• Python script that wraps VEP REST API or local install
• ClinVar and gnomAD annotation lookup
• Ancestry-stratified allele frequency reporting
• Markdown report + reproducibility bundle

Getting started

1. Read skills/vcf-annotator/SKILL.md for full specification
2. See skills/pharmgx-reporter/ or skills/nutrigx_advisor/ as reference implementations
3. Follow CONTRIBUTING.md for submission guidelines

🦖 Built with ClawBio