AudioContext.createChannelMerger()

var audioCtx = new AudioContext();
var merger = audioCtx.createChannelMerger(2);

var ac = new AudioContext();
ac.decodeAudioData(someStereoBuffer, function (data) {
  var source = ac.createBufferSource();
  source.buffer = data;
  var splitter = ac.createChannelSplitter(2);
  source.connect(splitter);
  var merger = ac.createChannelMerger(2);

  // Reduce the volume of the left channel only
  var gainNode = ac.createGain();
  gainNode.gain.value = 0.5;
  splitter.connect(gainNode, 0);

  // Connect the splitter back to the second input of the merger: we
  // effectively swap the channels, here, reversing the stereo image.
  gainNode.connect(merger, 0, 1);
  splitter.connect(merger, 1, 0);

  var dest = ac.createMediaStreamDestination();

  // Because we have used a ChannelMergerNode, we now have a stereo
  // MediaStream we can use to pipe the Web Audio graph to WebRTC,
  // MediaRecorder, etc.
  merger.connect(dest);
});